Protein S100-A9

BE0008993ProteinHumansS100A9

S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response (PubMed:12626582, PubMed:15331440, PubMed:16258195, PubMed:19122197, PubMed:20103766, PubMed:21325622, PubMed:8423249). It is acted on by 8 drugs in DrugBank.

Gene name
S100A9
UniProtKB entry
P06702Swiss-Prot
Cellular location
Secreted
Residues / weight
114 residues · 13,242 Da
Also known as
CAGB · Calgranulin-B · Calprotectin L1H subunit · CFAG · Leukocyte L1 complex heavy chain

Resolves to

Protein
UniProtP06702UniProt nameS10A9_HUMAN
Gene
HGNCHGNC:10499NCBI Gene6280GeneCardsS100A9
Pharmacology
KEGGhsa:6280
Structure
PDB1IRJPDB1XK4PDB4GGF
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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26GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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54+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein S100-A9, how selective are they, and which programs against it are still in active trials?

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