Dihydrofolate reductase

BE0009124ProteinStaphylococcus aureus (strain bovine RF122 / ET3-1)dfrB

Key enzyme in folate metabolism. It is acted on by 5 drugs in DrugBank.

Gene name
dfrB
UniProtKB entry
A0A0M3KKX1TrEMBL
Residues / weight
157 residues · 17,991 Da
Also known as
1.5.1.3

Resolves to

Protein
UniProtA0A0M3KKX1UniProt nameA0A0M3KKX1_STAAB
Structure
PDB4TU5
Drugs

What you can answer from here — as of September 04, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
6+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Dihydrofolate reductase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In