Tyrosine-protein kinase Blk

BE0009413ProteinHumansBLK

Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
BLK
UniProtKB entry
P51451Swiss-Prot
Cellular location
Cell membrane
Residues / weight
505 residues · 57,706 Da
Also known as
2.7.10.2 · B lymphocyte kinase · p55-Blk

Resolves to

Protein
UniProtP51451UniProt nameBLK_HUMAN
Gene
HGNCHGNC:1057NCBI Gene640GeneCardsBLK
Pharmacology
IUPHAR/GtoPdb1940KEGGhsa:640
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tyrosine-protein kinase Blk, how selective are they, and which programs against it are still in active trials?

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