Cyclin-G-associated kinase

BE0009445ProteinHumansGAK

Associates with cyclin G and CDK5. It is acted on by 3 drugs in DrugBank.

Gene name
GAK
UniProtKB entry
O14976Swiss-Prot
Cellular location
Cytoplasm, perinuclear region
Residues / weight
1,311 residues · 143,189 Da
Also known as
2.7.11.1 · Auxilin 2 · DnaJ homolog subfamily C member 26 · DNAJC26

Resolves to

Protein
UniProtO14976UniProt nameGAK_HUMAN
Gene
HGNCHGNC:4113NCBI Gene2580GeneCardsGAK
Pharmacology
IUPHAR/GtoPdb2027KEGGhsa:2580
Structure
PDB4C57PDB4C58PDB4C59
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cyclin-G-associated kinase, how selective are they, and which programs against it are still in active trials?

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