MAP kinase-interacting serine/threonine-protein kinase 1

BE0009488ProteinHumansMKNK1

May play a role in the response to environmental stress and cytokines. It is acted on by 3 drugs in DrugBank.

Gene name
MKNK1
UniProtKB entry
Q9BUB5Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
465 residues · 51,342 Da
Also known as
2.7.11.1 · MAP kinase signal-integrating kinase 1 · MAPK signal-integrating kinase 1 · MNK1

Resolves to

Protein
UniProtQ9BUB5UniProt nameMKNK1_HUMAN
Gene
HGNCHGNC:7110NCBI Gene8569GeneCardsMKNK1
Pharmacology
IUPHAR/GtoPdb2104KEGGhsa:8569
Structure
PDB2HW6PDB2Y9QPDB5WVD
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on MAP kinase-interacting serine/threonine-protein kinase 1, how selective are they, and which programs against it are still in active trials?

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