Tinodasertib

DB18796InvestigationalSmall molecule

Tinodasertib: Overview.

Mechanism: Pharmacologically active on MAP kinase-interacting serine/threonine-protein kinase 1 and MAP kinase-interacting serine/threonine-protein kinase 2
Curator reviewed
Formula / weight: C₂₅H₂₀N₄O₂ · 408.461 g/mol (avg)
Code names: AUM-001 · ETC-1907206 · ETC-206

Resolves to

Compound

UNIIMND3WX2R7ICAS1464151-33-4ChEMBLCHEMBL4211649

Structure

InChIKeyFWRFPHJSGLYXTD-UHFFFAOYSA-NSMILESO=C(N1CCOCC1)C1=CC=C(C=C1)C1=CN2C(C=C1)=NC=C2C1=CC=C(C=C1)C#N

Targets

Q9BUB5MKNK1Q9HBH9MKNK2

Transporters

Q9UNQ0ABCG2

What you can answer from here — as of July 09, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

12+ReferencesStructured and connected to the statements they support

Which drugs share a target with Tinodasertib, and which of those have an active Phase 3 trial?

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