Serine/threonine-protein kinase RIO1

BE0009528ProteinHumansRIOK1

Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. It is acted on by 2 drugs in DrugBank.

Gene name
RIOK1
UniProtKB entry
Q9BRS2Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
568 residues · 65,582 Da
Also known as
2.7.11.1 · 3.6.1.- · RIO kinase 1 · RIO1

Resolves to

Protein
UniProtQ9BRS2UniProt nameRIOK1_HUMAN
Gene
HGNCHGNC:18656NCBI Gene83732GeneCardsRIOK1
Pharmacology
KEGGhsa:83732
Structure
PDB4OTPPDB6G5IPDB6V0N
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase RIO1, how selective are they, and which programs against it are still in active trials?

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