Protein kinase C gamma type

BE0009588ProteinHumansPRKCG

Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to... It is acted on by 5 drugs in DrugBank.

Gene name
PRKCG
UniProtKB entry
P05129Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
697 residues · 78,447 Da
Also known as
2.7.11.13 · PKC-gamma · PKCG

Resolves to

Protein
UniProtP05129UniProt nameKPCG_HUMAN
Gene
HGNCHGNC:9402NCBI Gene5582GeneCardsPRKCG
Pharmacology
IUPHAR/GtoPdb1484KEGGhsa:5582
Structure
PDB2E73PDB2UZP
Drugs

What you can answer from here — as of September 03, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein kinase C gamma type, how selective are they, and which programs against it are still in active trials?

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