Aquaporin-3

BE0009664ProteinHumansAQP3

Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:12239222, PubMed:30420639). It is acted on by 6 drugs in DrugBank.

Gene name
AQP3
UniProtKB entry
Q92482Swiss-Prot
Cellular location
Cell membrane
Residues / weight
292 residues · 31,544 Da
Also known as
AQP-3 · Aquaglyceroporin-3

Resolves to

Protein
UniProtQ92482UniProt nameAQP3_HUMAN
Gene
HGNCHGNC:636NCBI Gene360GeneCardsAQP3
Pharmacology
IUPHAR/GtoPdb690KEGGhsa:360
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aquaporin-3, how selective are they, and which programs against it are still in active trials?

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