NADH-ubiquinone oxidoreductase chain 3

Details

Name
NADH-ubiquinone oxidoreductase chain 3
Kind
protein
Synonyms
  • 7.1.1.2
  • NADH dehydrogenase subunit 3
Gene Name
ND3
UniProtKB Entry
Q34522Swiss-Prot
Organism
Fasciola hepatica
NCBI Taxonomy ID
6192
Amino acid sequence
>lcl|BSEQ0052097|NADH-ubiquinone oxidoreductase chain 3
MLFFAVLGLLFFLIFFLVLVFHAFLWNLDLGIFSGERSWVSSFECGFLSQRVTENYFSYT
YFILLVFFVVFDLEVSLLLNMPLQGVLYKNFFSYLFFLVLLGIGFLVEVRRGYVRWAY
Number of residues
118
Molecular Weight
14031.585
Theoretical pI
Not Available
GO Classification
Functions
NADH dehydrogenase (ubiquinone) activity
Components
integral component of membrane / mitochondrial membrane / respirasome
General Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Specific Function
NADH dehydrogenase (ubiquinone) activity
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
1-21 59-79 86-106
Cellular Location
Mitochondrion membrane
Gene sequence
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ34522
UniProtKB Entry NameNU3M_FASHE
General References
  1. Garey JR, Wolstenholme DR: Platyhelminth mitochondrial DNA: evidence for early evolutionary origin of a tRNA(serAGN) that contains a dihydrouridine arm replacement loop, and of serine-specifying AGA and AGG codons. J Mol Evol. 1989 May;28(5):374-87. [Article]

Associated Data

Drug Relations
Not Available