Metal cation symporter ZIP14

BE0009903ProteinHumansSLC39A14

Electroneutral transporter of the plasma membrane mediating the cellular uptake of the divalent metal cations zinc, manganese and iron that are important for tissue homeostasis, metabolism, development and immunity (PubMed:15642354, PubMed:27231142, PubMed:29621230). It is acted on by 4 drugs in DrugBank.

Gene name
SLC39A14
UniProtKB entry
Q15043Swiss-Prot
Cellular location
Cell membrane
Residues / weight
492 residues · 54,212 Da
Also known as
KIAA0062 · LIV-1 subfamily of ZIP zinc transporter 4 · LZT-Hs4 · Solute carrier family 39 member 14 · ZIP-14

Resolves to

Protein
UniProtQ15043UniProt nameS39AE_HUMAN
Gene
HGNCHGNC:20858NCBI Gene23516GeneCardsSLC39A14
Pharmacology
KEGGhsa:23516
Drugs

What you can answer from here — as of September 03, 2024

4DrugsApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Metal cation symporter ZIP14, how selective are they, and which programs against it are still in active trials?

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