Apolipoprotein B-100

BE0009908ProteinHumansAPOB

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). It is acted on by 6 drugs in DrugBank.

Gene name
APOB
UniProtKB entry
P04114Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
4,563 residues · 515,540 Da
Also known as
Apo B-100

Resolves to

Protein
UniProtP04114UniProt nameAPOB_HUMAN
Gene
HGNCHGNC:603NCBI Gene338GeneCardsAPOB
Pharmacology
KEGGhsa:338
Structure
PDB9BD1PDB9BD8PDB9BDE
Drugs

What you can answer from here — as of April 13, 2020

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
22Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
40GO termsFunction, process and component, as structured annotations
Sign in
12Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
63+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Apolipoprotein B-100, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In