Free fatty acid receptor 3

BE0010132ProteinHumansFFAR3

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal... It is acted on by 2 drugs in DrugBank.

Gene name
FFAR3
UniProtKB entry
O14843Swiss-Prot
Cellular location
Cell membrane
Residues / weight
346 residues · 38,649 Da
Also known as
G protein-coupled receptor 41 · GPR41

Resolves to

Protein
UniProtO14843UniProt nameFFAR3_HUMAN
Gene
HGNCHGNC:4499NCBI Gene2865GeneCardsFFAR3
Pharmacology
IUPHAR/GtoPdb227KEGGhsa:2865
Structure
PDB8J20PDB8J21
Drugs

What you can answer from here — as of November 10, 2021

2DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Free fatty acid receptor 3, and which indications are they being tested in?

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