Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236 (completed for type 1 diabetes),...
- Mechanism
- Curator reviewed
Beta-hydroxybutyrate is a small molecule endogenous ketone body and metabolite synthesized in the liver from fatty acids. It is an energy carrier that moves energy from the liver to the peripheral tissues in times when glucose supply is too low for the energetic needs of the body. This ketone body has also been seen to have cellular signaling functions that link the outside environment to cellular function and epigenetic gene regulation. Beta-hydroxybutyrate has potential applications in a variety of diseases and human aging and is currently being investigated against COVID-19.
- Formula / weight
- C4H8O3 · 104.105 g/mol (avg)
- Also known as
- 3-HYDROXY-BUTANOIC ACID · 3-HYDROXYBUTYRIC ACID · Beta-Hydroxybutyrate · β-Hydroxybutyric acid
- Code names
- NSC-3806
Resolves to
WHBMMWSBFZVSSR-UHFFFAOYSA-NSMILESCC(O)CC(O)=OWhat you can answer from here — as of July 08, 2026
Which drugs share a target with beta-Hydroxybutyric acid, and which of those have an active Phase 3 trial?
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