This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Desoxyribonuclease
- DrugBank Accession Number
- DB09551
- Background
Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration 2.
- Type
- Biotech
- Groups
- Approved
- Synonyms
- Bovine pancreatic deoxyribonuclease
- Deoxyribonuclease A
- Deoxyribonuclease bovine pancreas
- Deoxyribonuclease I
- Deoxyribonuclease I bovine
- Deoxyribonuclease, bovine
- Dinase
- Pancreatic dornase
Pharmacology
- Indication
Not Available
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Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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Categories
- ATC Codes
- B06AA02 — Fibrinolysin and desoxyribonuclease
- B06AA — Enzymes
- B06A — OTHER HEMATOLOGICAL AGENTS
- B06 — OTHER HEMATOLOGICAL AGENTS
- B — BLOOD AND BLOOD FORMING ORGANS
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0BE71HM000
- CAS number
- 9003-98-9
References
- General References
- External Links
- PubChem Substance
- 347910461
- 3210
- Wikipedia
- Desoxyribonuclease
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Withdrawn Treatment Cystic Fibrosis (CF) / Sinusitis 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Ointment Cutaneous Solution Intramuscular 0.300 mg - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at November 30, 2015 19:10 / Updated at June 12, 2020 16:52