Neurotensin receptor type 1

BE0013004ProteinHumansNTSR1

G protein-coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:21725197, PubMed:23140271, PubMed:8381365). It is acted on by 3 drugs in DrugBank.

Gene name
NTSR1
UniProtKB entry
P30989Swiss-Prot
Cellular location
Cell membrane
Residues / weight
418 residues · 46,258 Da
Also known as
High-affinity levocabastine-insensitive neurotensin receptor · NT-R-1 · NTR1 · NTRH · NTRR

Resolves to

Protein
UniProtP30989UniProt nameNTR1_HUMAN
Gene
HGNCHGNC:8039NCBI Gene4923GeneCardsNTSR1
Pharmacology
IUPHAR/GtoPdb309KEGGhsa:4923
Structure
PDB2LYWPDB6OS9PDB6OSA
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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45GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Neurotensin receptor type 1, and which indications are they being tested in?

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