Neurotensin receptor type 1

BE0013004ProteinHumansNTSR1

G protein-coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:21725197, PubMed:23140271, PubMed:8381365). It is acted on by 3 drugs in DrugBank.

Gene name
NTSR1
UniProtKB entry
P30989Swiss-Prot
Cellular location
Cell membrane
Residues / weight
418 residues · 46,258 Da
Also known as
High-affinity levocabastine-insensitive neurotensin receptor · NT-R-1 · NTR1 · NTRH · NTRR

Resolves to

Protein
UniProtP30989UniProt nameNTR1_HUMAN
Gene
HGNCHGNC:8039NCBI Gene4923GeneCardsNTSR1
Pharmacology
IUPHAR/GtoPdb309KEGGhsa:4923
Structure
PDB2LYWPDB6OS9PDB6OSA
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Neurotensin receptor type 1, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In