Short transient receptor potential channel 1

BE0013282ProteinHumansTRPC1

Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:11139478, PubMed:15016832, PubMed:39478185). It is acted on by 3 drugs in DrugBank.

Gene name
TRPC1
UniProtKB entry
P48995Swiss-Prot
Cellular location
Cell membrane
Residues / weight
793 residues · 91,211 Da
Also known as
Transient receptor protein 1 · TRP-1 · TRP1 · TrpC1

Resolves to

Protein
UniProtP48995UniProt nameTRPC1_HUMAN
Gene
HGNCHGNC:12333NCBI Gene7220GeneCardsTRPC1
Pharmacology
KEGGhsa:7220
Structure
PDB8WPLPDB8WPMPDB9K4I
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Short transient receptor potential channel 1, and which indications are they being tested in?

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