Heat shock protein 75 kDa, mitochondrial

BE0014134ProteinHumansTRAP1

Chaperone that expresses an ATPase activity. It is acted on by 2 drugs in DrugBank.

Gene name
TRAP1
UniProtKB entry
Q12931Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
704 residues · 80,109 Da
Also known as
Heat shock protein family C member 5 · HSP 75 · HSP75 · HSPC5 · TNFR-associated protein 1

Resolves to

Protein
UniProtQ12931UniProt nameTRAP1_HUMAN
Gene
HGNCHGNC:16264NCBI Gene10131GeneCardsTRAP1
Pharmacology
IUPHAR/GtoPdb2909KEGGhsa:10131
Structure
PDB4Z1FPDB4Z1GPDB4Z1H
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Heat shock protein 75 kDa, mitochondrial, and which indications are they being tested in?

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