Phosphatidylcholine:ceramide cholinephosphotransferase 1

BE0016391ProteinHumansSGMS1

Major sphingomyelin synthase at the Golgi apparatus (PubMed:14685263, PubMed:17449912). It is acted on by 2 drugs in DrugBank.

Gene name
SGMS1
UniProtKB entry
Q86VZ5Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
413 residues · 48,617 Da
Also known as
2.7.8.27 · Medulla oblongata-derived protein · MOB · Protein Mob · SMS1

Resolves to

Protein
UniProtQ86VZ5UniProt nameSMS1_HUMAN
Gene
HGNCHGNC:29799NCBI Gene259230GeneCardsSGMS1
Pharmacology
IUPHAR/GtoPdb2520KEGGhsa:259230
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phosphatidylcholine:ceramide cholinephosphotransferase 1, and which indications are they being tested in?

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