Lysophosphatidic acid receptor 1

BE0017535ProteinHumansLPAR1

Receptor for lysophosphatidic acid (LPA) (PubMed:19306925, PubMed:25025571, PubMed:26091040, PubMed:9070858). It is acted on by 3 drugs in DrugBank.

Gene name
LPAR1
UniProtKB entry
Q92633Swiss-Prot
Cellular location
Cell surface
Residues / weight
364 residues · 41,109 Da
Also known as
EDG2 · LPA receptor 1 · LPA-1 · LPA1 · Lysophosphatidic acid receptor Edg-2

Resolves to

Protein
UniProtQ92633UniProt nameLPAR1_HUMAN
Gene
HGNCHGNC:3166NCBI Gene1902GeneCardsLPAR1
Pharmacology
IUPHAR/GtoPdb272KEGGhsa:1902
Structure
PDB4Z34PDB4Z35PDB4Z36
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Lysophosphatidic acid receptor 1, and which indications are they being tested in?

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