Monoglyceride lipase

BE0018885ProteinHumansMGLL

Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). It is acted on by 3 drugs in DrugBank.

Gene name
MGLL
UniProtKB entry
Q99685Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
303 residues · 33,261 Da
Also known as
3.1.1.23 · HU-K5 · Lysophospholipase homolog · Lysophospholipase-like · MAGL

Resolves to

Protein
UniProtQ99685UniProt nameMGLL_HUMAN
Gene
HGNCHGNC:17038NCBI Gene11343GeneCardsMGLL
Pharmacology
IUPHAR/GtoPdb1399KEGGhsa:11343
Structure
PDB3HJUPDB3JW8PDB3JWE
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Monoglyceride lipase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In