Monoglyceride lipase

BE0018885ProteinHumansMGLL

Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). It is acted on by 3 drugs in DrugBank.

Gene name
MGLL
UniProtKB entry
Q99685Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
303 residues · 33,261 Da
Also known as
3.1.1.23 · HU-K5 · Lysophospholipase homolog · Lysophospholipase-like · MAGL

Resolves to

Protein
UniProtQ99685UniProt nameMGLL_HUMAN
Gene
HGNCHGNC:17038NCBI Gene11343GeneCardsMGLL
Pharmacology
IUPHAR/GtoPdb1399KEGGhsa:11343
Structure
PDB3HJUPDB3JW8PDB3JWE
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Monoglyceride lipase, and which indications are they being tested in?

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