DB17049ExperimentalSmall molecule
Pristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.
- Mechanism
- Curator reviewed
Pharmacologically active on Inhibitor of nuclear factor kappa-B kinase subunit beta, Proteasome subunit beta type-5, and Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Formula / weight
- C30H40O4 · 464.646 g/mol (avg)
- Also known as
- (9.beta.,13.alpha.,14.beta.,20.alpha.)-3-hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid · 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, (9.beta.,13.alpha.,14.beta.,20.alpha.)- · Celastrol methyl ester
- Code names
- NSC-99281
Resolves to
Structure
InChIKey
JFACETXYABVHFD-WXPPGMDDSA-NSMILES[H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCWhat you can answer from here — as of July 08, 2026
4Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Pristimerin, and which of those have an active Phase 3 trial?
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