Serine/threonine-protein kinase pim-2

BE0020600ProteinHumansPIM2

Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. It is acted on by 6 drugs in DrugBank.

Gene name
PIM2
UniProtKB entry
Q9P1W9Swiss-Prot
Residues / weight
311 residues · 34,190 Da
Also known as
2.7.11.1 · Pim-2h

Resolves to

Protein
UniProtQ9P1W9UniProt namePIM2_HUMAN
Gene
HGNCHGNC:8987NCBI Gene11040GeneCardsPIM2
Pharmacology
IUPHAR/GtoPdb2159KEGGhsa:11040
Structure
PDB2IWIPDB4X7Q
Drugs

What you can answer from here — as of September 03, 2024

6DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Serine/threonine-protein kinase pim-2, and which indications are they being tested in?

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