Enolase

BE0027492ProteinStreptococcus mutans serotype c (strain ATCC 700610 / UA159)eno

Catalyzes the reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). It is acted on by 3 drugs in DrugBank.

Gene name
eno
UniProtKB entry
Q8DTS9Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
432 residues · 46,857 Da
Also known as
2-phospho-D-glycerate hydro-lyase · 2-phosphoglycerate dehydratase · 4.2.1.11

Resolves to

Protein
UniProtQ8DTS9UniProt nameENO_STRMU
Gene
NCBI Gene93859274
Pharmacology
KEGGsmu:SMU_1247
Drugs

What you can answer from here — as of April 22, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Enolase, how selective are they, and which programs against it are still in active trials?

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