Protein Precursors

Name
Protein Precursors
Accession Number
DBCAT000121
Description

Amino acids and chains of amino acids connected by peptide linkages.

Drugs
DrugDrug Description
GlucagonA form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures.
LiraglutideA GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes.
DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
BremelanotideBremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of...
SetmelanotideSetmelanotide is indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies or Bardet-Biedl syndrome.
ProcalcitoninProcalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD).
Fibrinogen humanA hemostatic agent used for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
Antihemophilic factor, human recombinantA form of recombinant coagulation Factor VIII used to treat hemophilia A, von Willebrand disease, and Factor XIII deficiency.
Drotrecogin alfaA form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.
Turoctocog alfaAn antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency).
Antihemophilic factor (recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
ThrombinA coagulation factor used to stop bleeding during surgery.
ProthrombinA coagulation factor used for emergency reversal of vitamin K antagonist therapy.
Protein CA medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
Factor IX Complex (Human)A Factor IX complex used to prevent and treat bleeding episodes in hemophilia B or vitamin K antagonist therapy.
Eftrenonacog alfaA recombinant Factor IX used to treat and prevent bleeding in hemophilia B.
Factor XIII (human)A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency.
Coagulation factor X humanA coagulation factor used to treat Factor X deficiency to control bleeding.
Coagulation factor VII humanA coagulation factor used to treat bleeding disorders such as hemophilia and Glanzmann's thrombasthenia.
Coagulation Factor IX HumanA coagulation factor used to treat hemophilia B or factor IX hemophilia.
Antihemophilic factor humanA Factor VIII replacement therapy used to treat hemophilia A.
Trenonacog alfaHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
Albutrepenonacog alfaA recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B.
Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
Moroctocog alfaA recombinant Factor VIII used to treat hemophilia A to control bleeding.
Beroctocog alfaBeroctocog alfa is indicated for the prevention and control of bleeding in patients with hemophilia A or acquired Factor VIII (FVIII) deficiency. It is also indicated for surgical/invasive procedures in...
Rurioctocog alfa pegolA pegylated recombinant human coagulation factor VIII used to treat and prevent bleeding episodes in patients 12 years and above with hemophilia A.
PlasminogenPlasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia).
Drugs & Drug Targets
DrugTargetType
GlucagonGlucagon receptortarget
GlucagonGlucagon-like peptide 2 receptortarget
GlucagonGlucagon-like peptide 1 receptortarget
LiraglutideGlucagon-like peptide 1 receptortarget
LiraglutideDipeptidyl peptidase 4enzyme
LiraglutideNeprilysinenzyme
LiraglutideSerum albumincarrier
DulaglutideGlucagon-like peptide 1 receptortarget
BremelanotideMelanocyte-stimulating hormone receptortarget
BremelanotideMelanocortin receptor 4target
BremelanotideMelanocortin receptor 3target
BremelanotideMelanocortin receptor 5target
BremelanotideAdrenocorticotropic hormone receptortarget
SetmelanotideMelanocortin receptor 4target
Antihemophilic factor, human recombinantCoagulation factor Xtarget
Antihemophilic factor, human recombinantPhytanoyl-CoA dioxygenase, peroxisomaltarget
Antihemophilic factor, human recombinantCoagulation factor IXtarget
Antihemophilic factor, human recombinantAsialoglycoprotein receptor 2target
Antihemophilic factor, human recombinant78 kDa glucose-regulated proteintarget
Antihemophilic factor, human recombinantCalreticulintarget
Antihemophilic factor, human recombinantCalnexintarget
Antihemophilic factor, human recombinantProtein ERGIC-53target
Antihemophilic factor, human recombinantProlow-density lipoprotein receptor-related protein 1target
Antihemophilic factor, human recombinantMultiple coagulation factor deficiency protein 2target
Antihemophilic factor, human recombinantvon Willebrand factortarget
Antihemophilic factor, human recombinantProthrombinenzyme
Antihemophilic factor, human recombinantVitamin K-dependent protein Cenzyme
Drotrecogin alfaCoagulation factor VIIItarget
Drotrecogin alfaCoagulation factor Vtarget
Drotrecogin alfaPlasminogen activator inhibitor 1target
Drotrecogin alfaThrombomodulintarget
Drotrecogin alfaVitamin K-dependent protein Starget
Drotrecogin alfaProthrombintarget
Drotrecogin alfaPlatelet factor 4target
Drotrecogin alfaPlasma serine protease inhibitortarget
Drotrecogin alfaSerpin B6target
Drotrecogin alfaEndothelial protein C receptortarget
Turoctocog alfaCoagulation factor IXtarget
Turoctocog alfaCoagulation factor Xtarget
Turoctocog alfaProthrombintarget
Antihemophilic factor (recombinant), PEGylatedvon Willebrand factortarget
Antihemophilic factor (recombinant), PEGylatedvon Willebrand factorcarrier
ThrombinProteinase-activated receptor 1target
ThrombinProteinase-activated receptor 4target
ThrombinCoagulation factor XItarget
ThrombinCoagulation factor XIII A chaintarget
ThrombinCoagulation factor XIII B chaintarget
ThrombinFibrinogen alpha chaintarget
ThrombinFibrinogen beta chaintarget
ThrombinFibrinogen gamma chaintarget
ThrombinCoagulation factor Vtarget
ThrombinCoagulation factor VIIItarget
ProthrombinFibrinogen alpha chaintarget
ProthrombinFibrinogen beta chaintarget
ProthrombinCoagulation factor XIII A chaintarget
ProthrombinCarboxypeptidase B2target
ProthrombinCoagulation factor Xenzyme
Protein CCoagulation factor Vtarget
Protein CCoagulation factor VIIItarget
Coagulation factor VII humanTissue factortarget
Coagulation factor VII humanCoagulation factor Xtarget
Coagulation factor VII humanCoagulation factor IXtarget
Coagulation Factor IX HumanCoagulation factor Xtarget
Coagulation Factor IX HumanCoagulation factor XItarget
Coagulation Factor IX HumanCoagulation factor VIItarget
Coagulation Factor IX HumanCoagulation factor VIIItarget
Coagulation Factor IX HumanProthrombintarget
Coagulation Factor IX HumanProlow-density lipoprotein receptor-related protein 1target
Coagulation Factor IX HumanVitamin K-dependent gamma-carboxylasetarget
Antihemophilic factor humanCoagulation factor IXtarget
Antihemophilic factor humanCoagulation factor Xtarget
Antihemophilic factor humanVitamin K-dependent protein Cenzyme
Albutrepenonacog alfaCoagulation factor Xtarget
Albutrepenonacog alfaCoagulation factor VIIIenzyme
Nonacog beta pegolCoagulation factor VIItarget
Nonacog beta pegolCoagulation factor VIIItarget
Nonacog beta pegolCoagulation factor Xtarget
Moroctocog alfaCoagulation factor Xtarget
Moroctocog alfaPhytanoyl-CoA dioxygenase, peroxisomaltarget
Moroctocog alfaCoagulation factor IXtarget
Moroctocog alfaAsialoglycoprotein receptor 2target
Moroctocog alfa78 kDa glucose-regulated proteintarget
Moroctocog alfaCalreticulintarget
Moroctocog alfaCalnexintarget
Moroctocog alfaProtein ERGIC-53target
Moroctocog alfaProlow-density lipoprotein receptor-related protein 1target
Moroctocog alfaMultiple coagulation factor deficiency protein 2target
Moroctocog alfavon Willebrand factortarget
Moroctocog alfaProthrombinenzyme
Moroctocog alfaVitamin K-dependent protein Cenzyme
Rurioctocog alfa pegolvon Willebrand factortarget
Rurioctocog alfa pegolCoagulation factor VIIItarget
PlasminogenTissue-type plasminogen activatorenzyme
PlasminogenUrokinase-type plasminogen activatorenzyme