- Amino Acids
- Accession Number
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
- ATC Classification
Drug Drug Description L-Lysine An amino acid commonly found as a component of total parenteral nutrition. Arginine An amino acid commonly found as a component of total parenteral nutrition. Aminocaproic acid An antifibrinolytic agent used to induce clotting postoperatively. L-Glutamine An amino acid commonly found as a component in total parenteral nutrition. Histidine An amino acid commonly found as a component of total parenteral nutrition. Ademetionine S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... Phenylalanine An amino acid commonly found as a component of total parenteral nutrition. Aspartic acid An amino acid commonly found as a component in total parenteral nutrition. Serine An amino acid commonly found as a component in total parenteral nutrition. Methionine An amino acid commonly found as a component in total parenteral nutrition. Tyrosine An amino acid commonly found as a component in total parenteral nutrition. Cystine An oxidated derivative of the amino acid cysteine found in various nutritional products and creams to treat cervical injury or inflammation. Glutamic acid An amino acid commonly found as a component in total parenteral nutrition. Glycine An amino acid commonly used as a component of total parenteral nutrition and is also used as irrigation during surgery. Creatine For nutritional supplementation, also for treating dietary shortage or imbalance. Leucine An amino acid commonly found as a component of total parenteral nutrition. Tryptophan An amino acid commonly found as a component of total parenteral nutrition. Cysteine An amino acid commonly found as a component of total parenteral nutrition and used as an antidote for acetaminophen overdose. Citrulline Used for nutritional supplementation, also for treating dietary shortage or imbalance. Threonine An amino acid commonly found as a component of total parenteral nutrition. Alanine An amino acid commonly found as a component of total parenteral nutrition. Valine An amino acid commonly found as a component of total parenteral nutrition. Isoleucine An amino acid commonly found as a component of total parenteral nutrition. Proline An amino acid commonly found as a component of total parenteral nutrition. Asparagine Used for nutritional supplementation, also for treating dietary shortage or imbalance. Baclofen A GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients. Pregabalin An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. Cycloserine A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). Promazine A phenothiazine used to manage schizophrenia. Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Dextrothyroxine A thyroid hormone used to treat hyperlipidemia. Valaciclovir An guanine nucleoside antiviral used to treat herpes exacerbations. Pemetrexed A folate analog used to treat mesothelioma and non-small cell lung cancer. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Metyrosine A tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma. Tirofiban A platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. Progabide Indicated for the treatment of epilepsy. Aminolevulinic acid A porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. Penicillamine A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis. Methyldopa An alpha-2 adrenergic agonist used to treat hypertension. Methyl aminolevulinate A porphyrin precursor used to treat non-hyperkeratotic, non-pigmented actinic keratosis of the face and scalp. Gabapentin An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. Melphalan An alkylating antineoplastic agent used to treat multiple myeloma and ovarian carcinoma. Mimosine Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca. Captopril An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. Ketamine A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. Stepronin Strepronin is a mucolytic (expectorant) drug. Liotrix May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... N-Acetylmethionine Not Available N,N-dimethylarginine Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which... Pantothenic acid A vitamin B5 found in various nutritional supplements. N-(Phosphonoacetyl)-L-Ornithine Not Available N,N-dimethylglycine Not Available Hadacidin Not Available Glycochenodeoxycholic Acid A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed.... S-Methylcysteine Not Available L-methionine (R)-S-oxide Not Available Glycinamide Ribonucleotide Not Available Selenocysteine A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and... Leucine Phosphonic Acid Not Available N-Acetylalanine Not Available Pyrrole-2-Carboxylate Not Available 4-Hydroxyphenylglycine Not Available D-Aspartic Acid The D-isomer of aspartic acid. [PubChem] N-(2-Acetamido)Iminodiacetic Acid Not Available Canaline Not Available 2-aminoisobutyric acid Not Available Oxitriptan For use as an antidepressant, appetite suppressant, and sleep aid. Beta-Hydroxyleucine Not Available Quisqualic acid Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular... Pidolic acid There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in... beta-Alanine beta-Alanine is an amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may... N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine Not Available N,O-Didansyl-L-Tyrosine Not Available Vinylglycine Vinylglycine is an irreversible inhibitor of aspartate aminotransferase. Diphthamide Not Available RWJ-51084 Not Available N-Acetylproline Not Available L-tyrosinamide Not Available Ubenimex An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia. 2s,4r-4-Methylglutamate Not Available N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. Sparfosic acid Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen... S-Phosphocysteine Not Available 3-Tyrosine Not Available Beta-Hydroxyaspartic Acid Not Available 4-Iodo-L-phenylalanine Not Available Bicine Not Available Trifluoromethionine Not Available L-2,4-diaminobutyric acid Not Available Batimastat Not Available Oxamic Acid Amino-substituted glyoxylic acid derivative. [PubChem] Phenylalanylamide Not Available Willardiine Willardiine is a compound isolated from seeds of Acacia willariana. Aceglutamide Not Available Norvaline Norvaline is an isomer of the more common amino acid valine. N(2)-(2-carboxyethyl)-L-arginine Not Available L-2-amino-3-butynoic acid Not Available Nitroarginine An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in... L-proline betaine Not Available Oxfenicine Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA). D-4-hydroxyphenylglycine Not Available 6-hydroxydopa quinone Not Available S-sulphocysteine Not Available Adenylosuccinic acid Not Available Alpha-Aminobutyric Acid Not Available N-Formylmethionine N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well... Paratoulene phosphate Not Available Aspartate Semialdehyde Not Available beta-Hydroxyasparagine Not Available Glyphosate Not Available Phenyldehydroalanine Not Available Cycloleucine Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments. Dansyllysine Not Available THIO-ATPA Not Available Roxadustat In clinical development for the treatment of anemia of chronic inflammatory disease. CDP323 Investigated for use/treatment in multiple sclerosis. INCB3284 Investigated for use/treatment in inflammatory disorders (unspecified). LX1031 Irritable bowel syndrome (IBS) and other gastrointestinal disorders WX-UK1 Investigated for use/treatment in solid tumors. Managlinat dialanetil Investigated for use/treatment in diabetes mellitus type 2. Alanosine Investigated for use/treatment in brain cancer and cancer/tumors (unspecified). Palifosfamide Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma. BL-1020 Investigated for use/treatment in schizophrenia and schizoaffective disorders. LY-517717 Investigated for use/treatment in thrombosis and venous thromboembolism. PPI-2458 Investigated for use/treatment in lymphoma (non-hodgkin's) and solid tumors. Acetylcysteine A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. Talotrexin Investigated for use/treatment in solid tumors, lung cancer, leukemia (unspecified), and leukemia (lymphoid). Eflornithine A medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin. Hexaminolevulinate An optical imaging agent used to perform Blue Light Cystoscopy (BLC™) in order to detect carcinoma of the bladder. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. GW-559090 Investigated for use/treatment in asthma and allergic rhinitis. Muraglitazar Investigated for use/treatment in diabetes mellitus type 2. Etilevodopa Investigated for use/treatment in parkinson's disease. Safinamide A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. Valrocemide Investigated for use/treatment in epilepsy. Carglumic acid An analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency. Lodoxamide An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. Tiopronin A thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. Z-Val-Ala-Asp fluoromethyl ketone Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the... N-BENZOYL-D-ALANINE Not Available Thiorphan A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms. Hydroxyproline Used in France as a combination product for the treatment of small, superficial wounds. Gabapentin enacarbil A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). Boceprevir A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. Arbaclofen Placarbil Investigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD. Technetium Tc-99m mebrofenin A diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests. Technetium Tc-99m disofenin A radiopharmaceutical diagnostic agent used for hepatobiliary scans. Clonixin Indicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. Azelnidipine For the treatment of hypertension. Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. Sacubitril A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Dexpanthenol An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). Ixazomib A monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already. N-acetyltyrosine An amino acid used in total parenteral nutrition. Selenomethionine Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can... Ferrous bisglycinate Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and... Levomefolic acid A folate supplement used to prevent neural tube defects in pregnancy or folate deficiency. Pidotimod For use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections . Cupric glycinate Not Annotated Lifitegrast A medication used to treat dry eye disease. Rebamipide Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer. Daprodustat Daprodustat has been used in trials studying the other, treatment, and basic science of Anaemia, Wound Healing, Tendon Injuries, Surgical Procedures, and Vascular Disease, Peripheral. Racecadotril Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis. Raxatrigine Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. Tosedostat Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the... Tilarginine Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow. Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. Astodrimer Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. Brivanib alaninate Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. Valbenazine A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia. Delanzomib Delanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin. Brivanib Brivanib is under investigation for the treatment of HepatoCellular Carcinoma. Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC). Nirogacestat Nirogacestat has been used in trials studying the treatment of Breast Cancer, HIV Infection, Desmoid Tumors, Advanced Solid Tumors, and Aggressive Fibromatosis, among others. MK-0893 MK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2. Telotristat ethyl A tryptophan hydroxylase inhibitor used to treat carcinoid syndrome. Rigosertib Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others. Bucillamine Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis. Oxothiazolidinecarboxylic acid Procysteine has been used in trials studying the treatment of HIV Infections. ORE-1001 ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor. Theanine Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD). Semagacestat Semagacestat has been used in trials studying the treatment of Alzheimer Disease. PD-217014 PD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome. Iofolastat I-123 Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer). Sarcosine Sarcosine has been investigated for the treatment of Schizophrenia. Decernotinib Decernotinib has been used in trials studying the treatment of Drug Interactions and Rheumatoid Arthritis. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Methylselenocysteine Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease. N-omega-nitro-L-arginine methyl ester L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury. Rabacfosadine Rabacfosadine has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin's Lymphoma, and Chronic Lymphocytic Leukemia. Indoximod Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others. Sivelestat Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult. Buthionine Sulfoximine Buthionine Sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin). AV-101 AV-101 has been used in trials studying the treatment of Neuropathic Pain. Ombrabulin Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms, Malignant, and Advanced Solid Tumors, among others. Pivagabine Pivagabine has been used in trials studying the treatment of Stress and Anxiety. Macimorelin A medication used to treat adult growth hormone deficiency. Tiropramide Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome). Zofenopril Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor. Phosphocreatine Phosphocreatine is a naturally occuring substance that is found predominantly in the skeletal muscles of vertebrates. Its primary utility within the body is to serve in the maintanence and recycling... Acetylleucine Used for treating vestibular-related imbalance and vertigo. Alaproclate Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity... Melevodopa Not Annotated Oxaceprol Not Annotated Proglumide Not Annotated Prethcamide Not Annotated Phenibut Not Annotated Calcium pangamate Not Annotated Aluminium glycinate Not Annotated Camylofin Not Annotated Paclitaxel poliglumex Not Annotated Netarsudil A rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension. Racemethionine A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. Nordazepam An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam. Tranexamic acid An antifibrinolytic agent used for heavy menstrual bleeding. Alanyl glutamine Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition). Aminomethylbenzoic acid Aminomethylbenzoic acid may be useful as an antifibrinolytic agent . Hopantenic acid Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... Methionine sulfoximine Not Annotated Sacubitrilat A metabolite of LCZ696 with neprilysin inhibitory activity. Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. Telotristat A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. Acetylcysteine amide Not Available Zinc glycinate Glycoprotein marker of gastrointestinal cancer. Zofenoprilat Not Available AB192 Investigated for use/treatment in diabetes mellitus type 2. Ornithine An amino acid commonly found as a component in total parenteral nutrition. S-adenosyl-L-homocysteine 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. gamma-Aminobutyric acid The most common inhibitory neurotransmitter in the central nervous system. Glycocholic acid The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycocyamine Not Available Tiratricol A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. 3-Methylglutamic acid Not Available Indantadol Indantadol has been used in trials studying the treatment of Cough and Diabetic Peripheral Neuropathic Pain. Glutamine hydroxamate Not Available 5-fluorotryptophan 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. Remdesivir A nucleoside analog used to treat RNA virus infections including COVID-19. Demplatin pegraglumer Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer). BMS-817399 BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis). GS-9191 GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts). Norleucine Norleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women). Amino acids Mixture of amino acids ; used for parenteral nutrition in infants. Panthenol An ingredient used in skin, hair care, and nutritional products but is not an approved medication. Vadadustat Vadadustat has been used in trials studying the treatment of Anemia and Non-dialysis-dependent Chronic Kidney Disease. PCI-27483 PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer. Fluorodopa (18F) Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes... Ivosidenib An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation. Solriamfetol Solriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744]. Adafosbuvir Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335). PF-06291874 PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus). Ciraparantag Ciraparantag is under investigation in clinical trial NCT01826266 (Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban). Canavanine Not Available L-homoarginine Not Available N-acetyl-L-arginine Not Available Thiocitrulline Not Available N(G)-Iminoethylornithine Not Available 5'-O-(N-(Alanyl)sulfamoyl)adenosine Not Available 5-Oxoprolinal Not Available Epsilon-N-methyllysine Not Available L-alloisoleucine Not Available p-Benzoyl-L-phenylalanine Not Available Tetraiodothyroacetic acid Not Available Kynurenine Not Available 4-methylthio-2-oxobutanoic acid Not Available 5'-S-methyl-5'-thioadenosine Not Available Symmetric dimethylarginine Not Available Allysine Not Available Cysteine-S-acetamide Not Available Isoglutamine Not Available 6-hydroxynorleucine Not Available N-hexadecanoylglycine Not Available L-serine O-sulfate Not Available 3-nitro-L-tyrosine Not Available S-Benzylcysteine Not Available Tryptophanamide Not Available Glycinamide Not Available L-methionine sulfone Not Available Trimethyllysine Not Available 1-Methylhistidine Not Available L-Saccharopine Not Available N-Carbamoylaspartic acid Not Available Homocysteine Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine. methyl L-phenylalaninate Not Available Fasitibant Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee). Ravidasvir Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection). Ketoprofen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. MK-0668 Not Annotated Desmeninol Not Annotated Acetylsalicylic acid A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. Carbocisteine Used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis. Ibuprofen An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. Gamma-amino-beta-hydroxybutyric acid Not Annotated Arginine aspartate Not Annotated TRC150094 TRC150094 is under investigation in clinical trial NCT03254446 (Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension). Denagliptin Denagliptin is under investigation in clinical trial NCT00387972 (Study of Denagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM)). Fasoracetam Fasoracetam is under investigation in clinical trial NCT03609619 (PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without Mglur Mutations). Racemetyrosine Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer). Dexfosfoserine The phosphoric acid ester of serine.
- Drugs & Drug Targets