- Membrane Lipids
- Accession Number
Lipids, predominantly phospholipids, cholesterol and small amounts of glycolipids found in membranes including cellular and intracellular membranes. These lipids may be arranged in bilayers in the membranes with integral proteins between the layers and peripheral proteins attached to the outside. Membrane lipids are required for active transport, several enzymatic activities and membrane formation.
Drug Drug Description Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Alfacalcidol A vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure, as well as some types of rickets and osteomalacia. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Soy sterol Not Annotated Phosphatidyl serine A nutrient used in some supplement products. Calcifediol An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients. Paricalcitol A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease. Dihydrotachysterol A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3. 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine Not Available Glycerol 2-phosphate Not Available Cholesterol sulfate Component of human seminal plasma & spermatozoa. Cholesteryl Linoleate Not Available Platelet Activating Factor Not Available Calcipotriol A topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. Lysophosphatidylglycerol Not Available Lexacalcitol Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known... sn-glycero-3-phosphoethanolamine Not Available Lanosterol Not Available Cadaverine Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine. Indole-3-Glycerol Phosphate Not Available Seocalcitol Not Available Phosphatidylethanolamine Not Available L-Dilinoleoyllecithin Not Available Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Choline alfoscerate A natural choline that is used to manage declining cognitive function associated with neurodegenerative and vascular diseases. 20-hydroxycholesterol Not Available 25-Hydroxycholesterol Not Available 7beta-hydroxycholesterol Not Available Sulfatide Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy. Inecalcitol Investigated for use/treatment in prostate cancer, psoriasis and hyperparathyroidism. Becocalcidiol For topical treatment of psoriasis and psoriatic disorders. Lucinactant Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. Pumactant Investigated for use/treatment in asthma, lung injury, and surgical adhesions. ETC-588 Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases. 1alpha,24S-Dihydroxyvitamin D2 Investigated for use/treatment in parathyroid disorders. Elocalcitol Investigated for use/treatment in benign prostatic hyperplasia, urinary incontinence, prostate disorders, and infertility. Maxacalcitol Not Annotated Doxercalciferol A synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Colfosceril palmitate A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Sodium glycerophosphate A medication used to treat hypophosphatemia. Calcium glycerophosphate An medication used to treat low levels of phosphate or calcium, as well as an ingredient in dental products to prevent dental caries. DL-dimyristoylphosphatidylcholine DL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication. DL-dimyristoylphosphatidylglycerol DL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications. KRN-7000 KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients... Siagoside Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a... 1alpha-Hydroxyvitamin D5 1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity. Iodine (131I) norcholesterol A radioiodine-labeled cholesterol analogue that accumulates in areas where steroid hormones are produced and is used in certain diagnostic procedures. Mifamurtide A muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection. Tacalcitol A vitamin D analog indicated in the treatment of mild to moderate plaque psoriasis. beta-Sitosterol Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity. 1,2-Distearoyllecithin Not Annotated Ceramide NP Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3... Ceramide AP Not Annotated Ceramide NG Not Annotated VB-201 VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis). 24-Homo-1,25-dihydroxyvitamin D3 24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue. Previtamin D(3) Not Annotated Lecithin Fatty substances commonly found in nutritional supplements. ABX-196 ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma). Iopofosine I-131 Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned). 24,25-Dihydroxycholecalciferol Not Annotated Larsucosterol Not Annotated CER-001 CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine Not Annotated CHF5633 CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
- Drugs & Drug Targets