Antifibrinolytic Agents

Name
Antifibrinolytic Agents
Accession Number
DBCAT000387
Description

Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.

Drugs
DrugDrug Description
Alpha-1-proteinase inhibitorA purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
Aminocaproic acidAn antifibrinolytic agent used to induce clotting postoperatively.
Aminomethylbenzoic acidAminomethylbenzoic acid may be useful as an antifibrinolytic agent .
AprotininA serine protease inhibitor used to reduce the risk for perioperative blood loss and the need for blood transfusion in high-risk patients during cardiopulmonary bypass for coronary artery bypass graft surgery.
CamostatA serine protease indicated in Japan to treat chronic pancreatitis.
Hydrogen peroxideA compound used as a disinfectant and sterilizer.
MenadioneThe primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
Menadione bisulfiteNot Annotated
Tranexamic acidAn antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders.
UlinastatinUlinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug.