Hydrogen peroxide

DB11091ApprovedInvestigationalVet approvedSmall moleculeAnti-Infective Agents, Local

Hydrogen peroxide is a compound used as a disinfectant and sterilizer. Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2.

Mechanism: The production of free hydroxyl radicals in the Fenton reaction is thought to be the basis of biocidal actions of hydrogen peroxide. Free radicals eventually lead to oxidative damage proteins and membrane lipids in vivo. The oxidizing radical as the ferryl radical induces DNA oxidation.
Curator reviewed · 2 references
Primary indication: Indicated to be used as a disinfectant and sterilizer.Curator reviewed · 4 structured indications
Formula / weight: H₂O₂ · 34.0147 g/mol (avg)
First approval: Canada, 1999 · United States, 1996
Code names: A-101 · NSC-19892
Brand names: Eskata
Orajel Mouth Sore Rinse

Resolves to

Compound

UNIIBBX060AN9VCAS7722-84-1ChEMBLCHEMBL71595ChEBI16240PubChem784KEGGC00027

Clinical / RWD

RxNorm5499ATCA01AB02ATCD08AX01ATCD11AX25

Structure

InChIKeyMHAJPDPJQMAIIY-UHFFFAOYSA-NSMILESOO

Targets

P18031PTPN1

What you can answer from here — as of March 06, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

58Drug interactionsStructured to mechanism, not free text

67Clinical trialsPhase, status and sponsor resolved per trial

4Structured indicationsCondition, population, route and combination as fields, not prose

464Marketed productsAcross 7 countries and 265 labellers

4ATC codesIncluding every combination product, plus 22 drug categories

13+ReferencesStructured and connected to the statements they support

Which drugs share a target with Hydrogen peroxide, and which of those have an active Phase 3 trial?

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