14-alpha Demethylase Inhibitors
- 14-alpha Demethylase Inhibitors
- Accession Number
Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
Drug Drug Description Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Voriconazole A triazole compound used to treat fungal infections. Miconazole An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. Tioconazole An imidazole antifungal used to treat vulvovaginal candidiasis. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Itraconazole An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. Econazole A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor. Posaconazole A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. Oteseconazole An azole antifungal used to prevent recurrent vulvovaginal candidiasis in females who are not of reproductive potential.
- Drugs & Drug Targets