Erythromycin and similars
- Name
- Erythromycin and similars
- Accession Number
- DBCAT000499
- Description
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
- ATC Classification
- Drugs
Drug Drug Description Erythromycin A macrolide antibiotic used to treat and prevent a variety of bacterial infections. Roxithromycin An antibiotic used to treat a variety of susceptible bacterial infections. Telithromycin An ketolide used to treat community acquired pneumonia of mild to moderate severity. Clarithromycin A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. Cethromycin A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia. Nafithromycin Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP). - Drugs & Drug Targets