Accession Number

Doubly unsaturated pregnane derivatives with two hydroxy groups substituted anywhere on the rings or side chains.

DrugDrug Description
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
MometasoneA corticosteroid with no indications.
FluocortoloneA glucocorticoid used topically for localized skin reactions and also orally for systemic use.
DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
Prednisone acetateNot Annotated
Fluocortolone pivalateA corticosteroid used to treat corticosteroid-responsive dermatoses and hemorrhoids.
Fluocortolone caproateA corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses.
ClocortoloneA corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
MeprednisoneNot Annotated
Clocortolone acetateNot Annotated
Drugs & Drug Targets
FluorometholoneCorticosteroid-binding globulincarrier
FluorometholoneCytochrome P450 3A4enzyme
FluorometholoneGlucocorticoid receptortarget
FluorometholoneCytochrome P450 3A5enzyme
DesoximetasoneGlucocorticoid receptortarget
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
MometasoneGlucocorticoid receptortarget
MometasoneCytochrome P450 2C8enzyme
MometasoneProgesterone receptortarget
MometasoneCytochrome P450 3A4enzyme
MometasoneCytochrome P450 3A5enzyme
FluocortoloneCytochrome P450 3A4enzyme
FluocortoloneCytochrome P450 3A5enzyme
DifluocortoloneAnnexin A3target
DifluocortoloneGlucocorticoid receptortarget
DifluocortoloneCytochrome P450 3A4enzyme
DifluocortoloneCytochrome P450 3A5enzyme
Prednisone acetateCytochrome P450 3A4enzyme
Prednisone acetateCytochrome P450 3A5enzyme
ClocortoloneGlucocorticoid receptortarget
MeprednisoneSerum albumincarrier
MeprednisoneCytochrome P450 3A4enzyme
MeprednisoneCytochrome P450 3A5enzyme
Clocortolone acetateCytochrome P450 3A4enzyme
Clocortolone acetateCytochrome P450 3A5enzyme