Phenylcarbamates

Name
Phenylcarbamates
Accession Number
DBCAT000848
Description

Phenyl esters of carbamic acid or of N-substituted carbamic acids. Structures are similar to PHENYLUREA COMPOUNDS with a carbamate in place of the urea.

Drugs
DrugDrug Description
MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
RivastigmineA cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's.
FelbamateAn anticonvulsant used to treat severe epilepsy.
PhysostigmineA cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
PhenserineFor the treatment of Alzheimer's disease (AD).
PosiphenPosiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Drugs & Drug Targets
DrugTargetType
MethocarbamolCarbonic anhydrase 1target
RivastigmineAcetylcholinesterasetarget
RivastigmineCholinesterasetarget
FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
FelbamateCytochrome P450 2C19enzyme
FelbamateCytochrome P450 3A4enzyme
FelbamateCytochrome P450 2E1enzyme
FelbamateCytochrome P450 2C9enzyme
PhysostigmineAcetylcholinesterasetarget
PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
PhenserineAcetylcholinesterasetarget
PhenserineCholinesterasetarget
PhenserineAmyloid-beta precursor proteintarget