Hallucinogens

Name
Hallucinogens
Accession Number
DBCAT000908
Description

Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.

Drugs
DrugDrug Description
4-MethoxyamphetamineNot Available
BrolamfetamineNot Available
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
DimethyltryptamineSome people use this compound as a psychedelic inducing agent.
DronabinolA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
HarmineNot Available
Lysergic acid diethylamideDebate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by...
MescalineMescaline is under investigation in clinical trial NCT05933213 (Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis).
MidomafetamineClinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used...
PhencyclidineA hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
PsilocybinPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Salvinorin ASalvinorin A has been investigated for the basic science of Pharmaceutical Preparations.
TenamfetamineAn amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons...
Drugs & Drug Targets
DrugTargetType
4-MethoxyamphetamineAlpha-1D adrenergic receptortarget
4-MethoxyamphetamineSynaptic vesicular amine transportertarget
4-MethoxyamphetamineAmine oxidase [flavin-containing] Btarget
4-MethoxyamphetamineAmine oxidase [flavin-containing] Atarget
4-MethoxyamphetamineSodium-dependent serotonin transportertarget
4-MethoxyamphetamineSodium-dependent dopamine transportertarget
4-MethoxyamphetamineCytochrome P450 2D6enzyme
4-MethoxyamphetamineAlpha-2A adrenergic receptortarget
4-MethoxyamphetamineAlpha-1A adrenergic receptortarget
Brolamfetamine5-hydroxytryptamine receptor 1Atarget
Brolamfetamine5-hydroxytryptamine receptor 2Atarget
Brolamfetamine5-hydroxytryptamine receptor 1Dtarget
Bufotenine5-hydroxytryptamine receptor 7target
Bufotenine5-hydroxytryptamine receptor 5Atarget
Bufotenine5-hydroxytryptamine receptor 6target
Bufotenine5-hydroxytryptamine receptor 2Atarget
Bufotenine5-hydroxytryptamine receptor 1Dtarget
BufotenineAmine oxidase [flavin-containing] Aenzyme
Dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
Dimethyltryptamine5-hydroxytryptamine receptor 6target
DimethyltryptamineSigma non-opioid intracellular receptor 1target
DronabinolUDP-glucuronosyltransferase 1A9enzyme
DronabinolUDP-glucuronosyltransferase 1A10enzyme
DronabinolMultidrug resistance-associated protein 1transporter
DronabinolCytochrome P450 3A7enzyme
DronabinolCytochrome P450 3A5enzyme
DronabinolCytochrome P450 2J2enzyme
DronabinolLiver carboxylesterase 1enzyme
DronabinolCytochrome P450 2D6enzyme
DronabinolUDP-glucuronosyltransferase 1A1enzyme
DronabinolCytochrome P450 3A4enzyme
DronabinolCytochrome P450 2C9enzyme
DronabinolCannabinoid receptor 1target
DronabinolCannabinoid receptor 2target
DronabinolATP-dependent translocase ABCB1transporter
DronabinolUDP-glucuronosyltransferase 1A3enzyme
DronabinolCytochrome P450 2B6enzyme
DronabinolCytochrome P450 2A6enzyme
DronabinolCytochrome P450 1B1enzyme
DronabinolCytochrome P450 1A2enzyme
DronabinolCytochrome P450 1A1enzyme
DronabinolCytochrome P450 2C19enzyme
DronabinolProstaglandin G/H synthase 1enzyme
DronabinolBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
HarmineDual specificity tyrosine-phosphorylation-regulated kinase 3target
HarmineDual specificity tyrosine-phosphorylation-regulated kinase 2target
HarmineDual specificity tyrosine-phosphorylation-regulated kinase 1Atarget
HarmineAmine oxidase [flavin-containing] Atarget
Lysergic acid diethylamide5-hydroxytryptamine receptor 1Atarget
Lysergic acid diethylamide5-hydroxytryptamine receptor 2Btarget
Lysergic acid diethylamideCytochrome P450 3A4enzyme
Lysergic acid diethylamideCytochrome P450 2D6enzyme
Lysergic acid diethylamide5-hydroxytryptamine receptor 2Atarget
Lysergic acid diethylamide5-hydroxytryptamine receptor 6target
Mescaline5-hydroxytryptamine receptor 2Atarget
MidomafetamineSodium-dependent serotonin transportertransporter
MidomafetamineSodium-dependent dopamine transportertransporter
MidomafetamineSodium-dependent noradrenaline transportertransporter
MidomafetamineSodium-dependent noradrenaline transportertarget
Midomafetamine5-hydroxytryptamine receptor 2Ctarget
Midomafetamine5-hydroxytryptamine receptor 2Btarget
Midomafetamine5-hydroxytryptamine receptor 2Atarget
MidomafetamineSodium-dependent dopamine transportertarget
MidomafetamineSynaptic vesicular amine transportertarget
MidomafetamineSodium-dependent serotonin transportertarget
MidomafetamineCytochrome P450 2D6enzyme
PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
PhencyclidineSigma non-opioid intracellular receptor 1target
PhencyclidineCytochrome P450 2B6enzyme
PhencyclidineGlutamate receptor ionotropic, NMDA 1target
PhencyclidineGlutamate receptor ionotropic, NMDA 2Btarget
PhencyclidineGlutamate receptor ionotropic, NMDA 2Atarget
Psilocybin5-hydroxytryptamine receptor 2Atarget
Salvinorin AMu-type opioid receptortarget
Salvinorin ADelta-type opioid receptortarget
Salvinorin AKappa-type opioid receptortarget
TenamfetamineSodium-dependent noradrenaline transportertarget
TenamfetamineSodium-dependent serotonin transportertarget
TenamfetamineSodium-dependent dopamine transportertarget