Alcohol Deterrents

Name
Alcohol Deterrents
Accession Number
DBCAT001048
Description

Substances interfering with the metabolism of ethyl alcohol, causing unpleasant side effects thought to discourage the drinking of alcoholic beverages. Alcohol deterrents are used in the treatment of alcoholism.

Drugs
DrugDrug Description
AcamprosateA medication used to maintain alcohol abstinence in patients with alcohol dependence.
DisulfiramA carbamate derivative used to treat alcohol addiction.
DaidzinNot Available
NaltrexoneA narcotic antagonist used in opioid overdose.
MetadoxineA medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy.
Drugs & Drug Targets
DrugTargetType
AcamprosateMetabotropic glutamate receptor 5target
AcamprosateSolute carrier family 22 member 6transporter
AcamprosateGlutamate (NMDA) receptortarget
AcamprosateGamma-aminobutyric acid type B receptor subunit 1target
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter
DaidzinAldehyde dehydrogenase, mitochondrialtarget
DaidzinATP-binding cassette sub-family G member 2transporter
NaltrexoneMu-type opioid receptortarget
NaltrexoneKappa-type opioid receptortarget
NaltrexoneDelta-type opioid receptortarget
NaltrexoneHCG20471, isoform CRA_ctarget
NaltrexoneUDP-glucuronosyltransferase 1-1enzyme