Amaryllidaceae Alkaloids

Accession Number

DBCAT001051

Description

Alkaloids derived from TYRAMINE combined with 3,4-dihydroxybenzaldehyde via a norbelladine pathway, including GALANTAMINE, lycorine and crinine. They are found in the Amaryllidaceae (LILIACEAE) plant family.

Drugs

Drug	Drug Description
Galantamine	A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.

Drugs & Drug Targets

Drug	Target	Type
Galantamine	Acetylcholinesterase	target
Galantamine	Cytochrome P450 3A4	enzyme
Galantamine	Cytochrome P450 2D6	enzyme
Galantamine	Cholinesterase	target
Galantamine	P-glycoprotein 1	transporter
Galantamine	Neuronal acetylcholine receptor subunit alpha-7	target
Galantamine	Muscle nicotinic acetylcholine receptor	target