Drug Delivery Systems
- Drug Delivery Systems
- Accession Number
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
Drug Drug Description Amphotericin B An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Carbetocin An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. Propylene glycol A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. Tromethamine A proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery. AP5280 Investigated for use/treatment in solid tumors. Tragacanth An extract from Tragacanth used in allergy testing. Polysorbate 80 It is used as a solubilizer, antimicrobial preservative and disinfectant . Polysorbate 20 Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is... Poloxamer 407 Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,... Poloxamer 188 A medication used to clean wounds. Astodrimer Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. Tricaprylin Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease. Microcrystalline cellulose A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,... Poly(lactic acid) Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy). Hydroxypropyl betadex Hydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C). Polyethylene glycol A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. Triethylhexanoin Triethylhexanoin is an ingredient of cosmetic products as a fragrant solvent.
- Drugs & Drug Targets
Drug Target Type Amphotericin B Ergosterol target Carbetocin Oxytocin receptor target Propylene glycol B12-independent glycerol dehydratase target Tromethamine Amyloid beta A4 protein target Astodrimer Envelope glycoprotein gp160 target Polyethylene glycol P-glycoprotein 1 transporter