Polyethylene Glycols

Name
Polyethylene Glycols
Accession Number
DBCAT001605
Description

Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.

ATC Classification
Drugs
DrugDrug Description
SP1049CIntended for the treatment of carcinoma of the oesophagus.
OnerceptInvestigated for use/treatment in psoriasis and psoriatic disorders and crohn's disease.
Nonoxynol-9A vaginal spermicide used for the non-hormonal contraception in conjunction with other modes of contraception.
Certolizumab pegolA tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant .
Polysorbate 20Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is...
Poloxamer 407Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,...
Poloxamer 188A medication used to clean wounds.
PoloxaleneEthylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen...
Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
PolidocanolA sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
Nanoparticle EpirubicinNanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).
Drugs & Drug Targets
DrugTargetType
SP1049CDNA topoisomerase 2-alphatarget
OnerceptTumor necrosis factortarget
Nonoxynol-9Prostaglandin G/H synthase 2enzyme
Certolizumab pegolTumor necrosis factortarget
Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
Polyethylene glycolP-glycoprotein 1transporter