Poloxamer 407

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Poloxamer 407
DrugBank Accession Number
DB11252
Background

Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. Poloxamer 407 is used as an emulsifying agent and solubilizing agent in cosmetic and personal products such as contact lens cleaning solutions.

Type
Small Molecule
Groups
Investigational
Synonyms
Not Available

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Dream EyeLiquid0.1 mL/1mLOphthalmicK&J.C Co., Ltd2010-10-13Not applicableUS flag
Dream EyeLiquid0.1 mL/1mLOphthalmicK&J.C Co., Ltd2010-06-17Not applicableUS flag
K-MOM Baby ToothPaste, dentifrice2 g/100gDentalMOTHER-K CO.,LTD2019-10-01Not applicableUS flag
Natural CareLiquid0.1 mL/1mLOphthalmicK&J.C Co., Ltd2010-10-05Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
อลิซ คอมฟอร์ท มัลติ-เพอพัส โซลูชั่นPoloxamer 407 (0.05 g/100ml) + Boric acid (0.175 g/100ml) + Edetate disodium (0.1 g/100ml) + Hypromellose (0.15 g/100ml) + Polyaminopropyl biguanide (0.00015 g/100ml) + Sodium borate (0.079 g/100ml) + Sodium chloride (0.83 g/100ml)SolutionOphthalmicบริษัท อลิซไลฟ์ จำกัด จำกัด2017-02-022020-09-29Thailand flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Dream EyePoloxamer 407 (0.1 mL/1mL)LiquidOphthalmicK&J.C Co., Ltd2010-10-13Not applicableUS flag
Dream EyePoloxamer 407 (0.1 mL/1mL)LiquidOphthalmicK&J.C Co., Ltd2010-06-17Not applicableUS flag
K-MOM Baby ToothPoloxamer 407 (2 g/100g)Paste, dentifriceDentalMOTHER-K CO.,LTD2019-10-01Not applicableUS flag
Natural CarePoloxamer 407 (0.1 mL/1mL)LiquidOphthalmicK&J.C Co., Ltd2010-10-05Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
TUF2IVW3M2
CAS number
691397-13-4

References

General References
Not Available
PubChem Substance
347911166
RxNav
155155
Wikipedia
Poloxamer_407

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedSupportive CareOral Mucositis1
2TerminatedTreatmentPersistent Corneal Epithelial Defects1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Paste, dentifriceDental2 g/100g
LiquidOphthalmic0.1 mL/1mL
SolutionOphthalmic
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53