Integrase Inhibitors

Name
Integrase Inhibitors
Accession Number
DBCAT001872
Description

Compounds which inhibit or antagonize biosynthesis or actions of integrase.

Drugs
DrugDrug Description
RaltegravirAn antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
DolutegravirAn antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
HIV Integrase InhibitorHIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).
Drugs & Drug Targets
DrugTargetType
RaltegravirUDP-glucuronosyltransferase 1-1enzyme
RaltegravirIntegrasetarget
DolutegravirUDP-glucuronosyltransferase 1-1enzyme
DolutegravirCytochrome P450 3A Subfamilyenzyme
DolutegravirIntegrasetarget
DolutegravirSolute carrier family 22 member 2transporter
DolutegravirUDP-glucuronosyltransferase 1-3enzyme
DolutegravirUDP-glucuronosyltransferase 1-9enzyme
DolutegravirATP-binding cassette sub-family G member 2transporter
DolutegravirSolute carrier family 22 member 6transporter
DolutegravirSolute carrier family 22 member 8transporter
DolutegravirP-glycoprotein 1transporter