GLP-1 Agonists

Name
GLP-1 Agonists
Accession Number
DBCAT002693  (DBCAT003437, DBCAT003869, DBCAT004144)
Description

Glucagon-like peptide-1 receptor agonists also known as GLP-1 receptor agonists or incretin mimetics are agonists of the GLP-1 receptor. This class of drugs is used for the treatment of type 2 diabetes.

Drugs
DrugDrug Description
ExenatideA GLP-1 agonist used in the management of type 2 diabetes mellitus.
LiraglutideA GLP-1 analog used in the management of type 2 diabetes mellitus, prevention of cardiovascular complications associated with diabetes, and obesity.
AlbiglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
TaspoglutideTaspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche. In September 2010 Roche halted...
LixisenatideA GLP-1 receptor agonist used for the management of type 2 diabetes mellitus.
SemaglutideA glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus, treat obesity, and reduce the risk of major adverse cardiovascular events in selected adults.
TirzepatideA dual GIP and GLP-1 receptor agonist used for the treatment of type II diabetes in adults as an adjunct to diet and exercise.
Drugs & Drug Targets
DrugTargetType
ExenatideGlucagon-like peptide 1 receptortarget
ExenatideAlbumincarrier
ExenatideDipeptidyl peptidase 4enzyme
LiraglutideGlucagon-like peptide 1 receptortarget
LiraglutideDipeptidyl peptidase 4enzyme
LiraglutideNeprilysinenzyme
LiraglutideAlbumincarrier
AlbiglutideGlucagon-like peptide 1 receptortarget
DulaglutideGlucagon-like peptide 1 receptortarget
TaspoglutideGlucagon-like peptide 1 receptortarget
LixisenatideGlucagon-like peptide 1 receptortarget
SemaglutideAlbumincarrier
SemaglutideDipeptidyl peptidase 4enzyme
SemaglutideNeprilysinenzyme
SemaglutideGlucagon-like peptide 1 receptortarget
SemaglutideLipoprotein lipaseenzyme
TirzepatideGlucagon-like peptide 1 receptortarget
TirzepatideAlbumincarrier
TirzepatideGastric inhibitory polypeptide receptortarget