Nitrates and Nitrites

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Name: Nitrates and Nitrites
Accession Number: DBCAT003688
Description: Not Available
Drugs: Drug Drug Description
Isosorbide dinitrate A vasodilator used to treat angina in coronary artery disease.
Isosorbide mononitrate A nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
Nitroglycerin A nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures.
Nitroprusside A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
Drugs & Drug Targets: Drug Target Type
Isosorbide dinitrate Atrial natriuretic peptide receptor 1 target
Isosorbide dinitrate Cytochrome P450 2E1 enzyme
Isosorbide mononitrate Guanylate cyclase soluble subunit alpha-2 target
Isosorbide mononitrate Glutathione S-transferase Mu 1 enzyme
Isosorbide mononitrate Xanthine dehydrogenase/oxidase enzyme
Isosorbide mononitrate Alcohol dehydrogenase class-3 enzyme
Nitric Oxide Guanylate cyclase soluble subunit alpha-2 target
Nitric Oxide Aldehyde dehydrogenase, mitochondrial enzyme
Nitric Oxide Cytochrome P450 1A2 enzyme
Nitric Oxide Cytochrome P450 2B6 enzyme
Nitric Oxide Cytochrome P450 3A4 enzyme
Nitric Oxide Metallothionein-1A target
Nitric Oxide Indoleamine 2,3-dioxygenase 1 target
Nitric Oxide Nitric oxide synthase 3 target
Nitric Oxide Guanylate cyclase soluble subunit alpha-1 target
Nitric Oxide Guanylate cyclase soluble subunit beta-1 target
Nitroglycerin Atrial natriuretic peptide receptor 1 target
Nitroglycerin Aldehyde dehydrogenase, mitochondrial enzyme
Nitroglycerin Epidermal growth factor receptor target
Nitroglycerin Guanylate cyclase soluble subunit alpha-1 target
Nitroglycerin Guanylate cyclase soluble subunit beta-1 target
Nitroprusside Atrial natriuretic peptide receptor 1 target
Nitroprusside Cytochrome P450 1A1 enzyme
Nitroprusside Guanylate cyclase soluble subunit alpha-1 target
Nitroprusside Guanylate cyclase soluble subunit beta-1 target
Nitroprusside Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 target
Nitroprusside Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 target
Nitroprusside Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 target

Drug	Drug Description
Isosorbide dinitrate	A vasodilator used to treat angina in coronary artery disease.
Isosorbide mononitrate	A nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
Nitric Oxide	A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
Nitroglycerin	A nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures.
Nitroprusside	A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.

Nitrates and Nitrites

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