Iron Chelating Activity

Name
Iron Chelating Activity
Accession Number
DBCAT004279
Description

Not Available

Drugs
DrugDrug Description
DeferiproneAn iron chelator used to treat patients with transfusional iron overload caused by thalassemia syndromes.
DeferoxamineA chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias.
DeferasiroxAn iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
Edetate calcium disodium anhydrousA chelating agent used to treat lead poisoning.
Drugs & Drug Targets
DrugTargetType
DeferiproneUDP-glucuronosyltransferase 1-6enzyme
DeferiproneIrontarget
DeferoxamineXanthine dehydrogenase/oxidaseenzyme
DeferoxamineIrontarget
DeferoxamineAluminumtarget
DeferoxamineAmyloid-beta precursor proteintarget
DeferasiroxIrontarget
DeferasiroxCytochrome P450 3A4enzyme
DeferasiroxUDP-glucuronosyltransferase 1A1enzyme
DeferasiroxUDP-glucuronosyltransferase 1A3enzyme
DeferasiroxUDP-glucuronosyltransferase 1A9enzyme
DeferasiroxCytochrome P450 2C8enzyme
DeferasiroxCytochrome P450 1A2enzyme
Edetate calcium disodium anhydrousManganese cationtarget
Edetate calcium disodium anhydrousIrontarget
Edetate calcium disodium anhydrousLeadtarget
Edetate calcium disodium anhydrousAdenosine deaminaseenzyme
Edetate calcium disodium anhydrousSerum paraoxonase/lactonase 3enzyme
Edetate calcium disodium anhydrousAromataseenzyme
Edetate calcium disodium anhydrousCytochrome P450 3A4enzyme
Edetate calcium disodium anhydrousSerum paraoxonase/arylesterase 1enzyme