Decreased GnRH Secretion

Name
Decreased GnRH Secretion
Accession Number
DBCAT004322
Description

Not Available

Drugs
DrugDrug Description
GanirelixA GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges.
CetrorelixA synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy.
DegarelixA GnRH receptor antagonist used in the management of advanced prostate cancer.
ElagolixA gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis.
RelugolixAn oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.
Drugs & Drug Targets
DrugTargetType
GanirelixGonadotropin-releasing hormone receptortarget
CetrorelixLutropin-choriogonadotropic hormone receptortarget
CetrorelixGonadotropin-releasing hormone receptortarget
DegarelixGonadotropin-releasing hormone receptortarget
ElagolixGonadotropin-releasing hormone receptortarget
ElagolixCytochrome P450 3A Subfamilyenzyme
ElagolixCytochrome P450 2D6enzyme
ElagolixCytochrome P450 2C8enzyme
ElagolixP-glycoprotein 1transporter
ElagolixSolute carrier organic anion transporter family member 1B1transporter
RelugolixSerum albumincarrier
RelugolixAlpha-1-acid glycoprotein 1carrier
RelugolixP-glycoprotein 1transporter
RelugolixATP-binding cassette sub-family G member 2transporter
RelugolixCytochrome P450 3A Subfamilyenzyme
RelugolixCytochrome P450 2C8enzyme
RelugolixCytochrome P450 2B6enzyme
RelugolixGonadotropin-releasing hormone receptortarget