Cytidine Deaminase Substrates
- Cytidine Deaminase Substrates
- Accession Number
Molecules that are metabolized by cytidine deaminase (CDA).
Drug Drug Description Gemcitabine A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. Cytarabine A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia. Azacitidine A pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome. Capecitabine A nucleoside metabolic inhibitor indicated to treat colon, colorectal and breast cancer. Decitabine A chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
- Drugs & Drug Targets