Bispecific Monoclonal Antibodies

Name
Bispecific Monoclonal Antibodies
Accession Number
DBCAT005664
Description

A monoclonal antibody that can simultaneously bind to two different types of antigen or epitopes.

Drugs
DrugDrug Description
AmivantamabAn EGF and MET receptor targeted antibody indicated in the treatment of non-small cell lung cancer with an EGFR 20 exon insertion mutation.
CatumaxomabFor use in the management of malignant ascites tumours via intraperitoneal infusion where standard therapy is not available or feasible [FDA Label].
TeclistamabA bispecific B-cell maturation antigen (BCMA)-directed CD3 T cell engager used to treat relapsed and refractory multiple myeloma in adults as monotherapy.
GlofitamabA bispecific monoclonal antibody directed against CD20 and CD3 which is used for the treatment of relapsed or refractory diffuse large B-cell lymphoma.
EpcoritamabA bispecific CD20-directed CD3 T-cell engager used to treat relapsed or refractory diffuse large B-cell lymphoma (DLBCL) in adults.
TalquetamabA bispecific antibody used to treat adults with relapsed or refractory multiple myeloma.
ElranatamabA bispecific antibody used to treat adults with relapsed or refractory multiple myeloma.
Drugs & Drug Targets
DrugTargetType
AmivantamabEpidermal growth factor receptortarget
AmivantamabHepatocyte growth factor receptortarget
AmivantamabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
CatumaxomabEpithelial cell adhesion moleculetarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor II-atarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
CatumaxomabT-cell surface glycoprotein CD3 epsilon chaintarget
CatumaxomabHigh affinity immunoglobulin gamma Fc receptor Itarget
TeclistamabT-cell surface glycoprotein CD3target
TeclistamabTumor necrosis factor receptor superfamily member 17target
GlofitamabB-lymphocyte antigen CD20target
GlofitamabT-cell surface glycoprotein CD3target
EpcoritamabB-lymphocyte antigen CD20target
EpcoritamabT-cell surface glycoprotein CD3 epsilon chaintarget
TalquetamabT-cell surface glycoprotein CD3target
TalquetamabG-protein coupled receptor family C group 5 member Dtarget
ElranatamabTumor necrosis factor receptor superfamily member 17target
ElranatamabT-cell surface glycoprotein CD3target