Candidemia (DBCOND0000135)

Identifiers

Synonyms
Candidaemia / Candida fungemia / Candidemia (disorder) / Candidal sepsis / Systemic moniliasis / Systemic candida / Disseminated candidiasis (disorder) / Systemic candidiasis / Disseminated candidiasis

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Anidulafungin
An antifungal used in the treatment of several types of candida infections.
Caspofungin
An echinocandin used to treat a variety of fungal infections.
Fluconazole
A triazole antifungal used to treat various fungal infections including candidiasis.
Micafungin
An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
Rezafungin
An echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis.
Voriconazole
A triazole compound used to treat fungal infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00509834
A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Proven Candidaemiatreatment1 / 2withdrawn
NCT01174147
A Laboratory-based Surveillance Study of Candida Bloodstream Infections (MK-0991-093)No drug interventionsNot AvailableNot Availablecompleted
NCT01281345
SIHAM Candidemia Network:An Observational StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01406093
Early- and Late-onset CandidemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02244606
Oral Ibrexafungerp (SCY-078) vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasistreatment2completed
NCT01249313
Risk Factor and Outcome of CandidemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00413218
Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infectionstreatment3completed
NCT03363841
Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES)treatment3completed
NCT00940017
A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy SubjectsNot Available4completed
NCT00739934
Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infectiontreatment2completed
NCT00607763
Study of Mycamine® in Infants and Toddlers With Fungal Infections to Evaluate Safety and Blood Levels of the DrugNot Available1completed
NCT01734525
Negative Beta Glucan in ICU Patientstreatment4completed
NCT00670657
CRITIC - Treatment of Candidemia and Invasive Candidiasistreatment4completed
NCT00903526
Prevalence and Epidemiology of Nosocomial Candidaemia and Antifungal Susceptibility Patterns in an Italian Tertiary-Care HospitalNo drug interventionsNot AvailableNot Availableunknown_status
NCT02333266
Bio-assay Development and Implementation for Fungal Infection DetectionNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02088476
Candidemia in a Pediatric Center and Importance of Central Venous Catheter RemovalNo drug interventionsNot AvailableNot Availablecompleted
NCT00113191
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature InfantsNo drug interventionspreventionNot Availablecompleted
NCT00548262
This Is An Open-Label, Non-Comparative Study Designed To Evaluate A Short Course Of IV Anidulafungin, Followed Optionally By Oral Voriconazole, For The Treatment Of Candidemia And Invasive Candidiasistreatment4completed
NCT02734862
CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extensiontreatment2completed
NCT05178862
A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazoletreatment3suspended
NCT02163889
Serial Therapeutic and Antifungal Monitoring ProtocolNo drug interventionsNot AvailableNot Availablecompleted
NCT00105144
Study of Micafungin in Patients With Invasive Candidiasis or Candidemiatreatment3completed
NCT02841501
Genetic Susceptibility Factors for Candidemia.No drug interventionsNot AvailableNot Availablecompleted
NCT03667690
Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasistreatment3completed
NCT04148287
An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auristreatment2completed
NCT00802854
Post Marketing Surveillance Study To Observe Safety And Efficacy Of Eraxis® IVNo drug interventionsNot AvailableNot Availablecompleted
NCT03604705
An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemiatreatment2completed
NCT01982071
A Study to Evaluate the Efficacy and Safety of Micafungin Against Invasive Candidiasis or Candidemiatreatment4terminated
NCT00189709
Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemiatreatment3completed
NCT04979052
Safety and Efficacy of Interferon-Gamma 1b in Patients With Candidemiatreatment2recruiting
NCT04368559
Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantationprevention3recruiting
NCT04147975
Assessment of Assay for Rapid Identification of Bloodstream Infections From Whole BloodNo drug interventionsNot AvailableNot Availableunknown_status
NCT01438216
Anidulafungin Pharmacokinetics in Intensive Care Unit PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05421858
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.treatment3not_yet_recruiting
NCT01176058
A Study Of The Efficacy And Safety Of Anidulafungin Vs. Fluconazole In The Treatment Of Patients With Candidemia And/Or Other Forms Of Invasive CandidiasisNot Available3terminated
NCT00608335
Study of Mycamine® in Children With Fungal Infections to Evaluate Safety and Blood Levels of the Drugother1completed
NCT01752166
Detecting Infections Rapidly and Easily for Candidemia Trial - Part 2 (direcT2 Study)No drug interventionsNot AvailableNot Availablecompleted
NCT00537329
Anidulafungin In Treatment Of Candidemia In Asian Subjectstreatment3completed
NCT00839540
Comparison of Candida Eradication and Serum Cidal Activity of Echinocandinstreatment4completed
NCT00761267
Study To Assess Pharmacokinetics, Safety & Efficacy of Anidulafungin When Treating Children With Invasive Candidiasistreatment3completed
NCT03799172
Echinocandins Versus Azoles for Candidemia TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01622595
UARK 2009-99 A Non-interventional Observational Study of Infectious Complications in Cancer PatientsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01525095
Detecting Infections Rapidly and Easily for Candidemia Trial (DIRECT)No drug interventionsNot AvailableNot Availablecompleted
NCT01213823
Risk Of Severe Hepatic Injury In Patients With Invasive Candidiasis Treated With EchinocandinsNo drug interventionsNot AvailableNot Availableterminated
NCT01270490
Efficacy of Interferon-gamma in Combination With Anidulafungin for the Treatment of Candidemiatreatment3unknown_status
NCT03827330
Retrospective Chart Review of Candida FungemiaNo drug interventionsNot AvailableNot Availablecompleted