NCT00727090
Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients treatment 4 terminated NCT04035564
Early Sodium Intake in Preterm Newborns No drug interventions prevention 4 completed NCT01299779
Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS Not Available Not Available completed NCT04744987
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia No drug interventions Not Available Not Available completed NCT02666651
Regional Tolvaptan Registry treatment 4 unknown_status NCT02667977
Reexamining Hypotonic Intravenous Fluid Use No drug interventions prevention Not Available withdrawn NCT02573077
An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in Italy No drug interventions Not Available Not Available completed NCT03032445
Beer for Endurance Exercise Recovery No drug interventions treatment Not Available completed NCT02548845
An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain No drug interventions Not Available Not Available completed NCT02084797
V2 Receptor Effects on Fluid Regulation and Performance Not Available Not Available completed NCT02765061
Hyponatremia and Hypoalbuminemia is Morbimortality Predictors in Coronary Artery Bypass Graft Surgery No drug interventions Not Available Not Available completed NCT02959411
Tolvaptan for Advanced or Refractory Heart Failure treatment 4 terminated NCT01212211
Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy? No drug interventions prevention Not Available completed NCT01716611
Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites treatment 4 unknown_status NCT02020278
An Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euvolemic or Hypervolemic Hyponatremia treatment 3 terminated NCT03787888
Hyponatremia Due to Poly Ethylene Glycol (PEG) No drug interventions Not Available Not Available completed NCT06498856
Saline Infusion Test in Hyponatremia No drug interventions Not Available Not Available not_yet_recruiting NCT01456832
Post Operative Hyponatremia in the Renal Transplant Population No drug interventions Not Available Not Available completed NCT06109532
Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation. No drug interventions Not Available Not Available recruiting NCT06171100
Low-dose Tolvaptan for Inpatient Hyponatraemia. Not Available Not Available recruiting NCT02012959
Study of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia treatment 3 terminated NCT00550459
Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients treatment 3 completed NCT01838759
Bioimpedance Spectroscopy for the Differential Diagnosis of Hyponatremia No drug interventions Not Available Not Available completed NCT00632775
0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children treatment 3 completed NCT01251770
Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children No drug interventions treatment 3 completed NCT03371199
The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy. prevention Not Available completed NCT04119206
Tolvaptan Versus Fluid Restriction in SIADH No drug interventions Not Available Not Available completed NCT00032734
Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion treatment 2 completed NCT00839358
Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation prevention 4 completed NCT02399358
Factors Associated With Hyponatremia Induced by High-dose Cyclophosphamide No drug interventions Not Available Not Available unknown_status NCT02727686
Post-Operative Water Load Following Transsphenoidal Pituitary Surgery No drug interventions supportive_care Not Available completed NCT00843986
Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF) treatment 3 terminated NCT04022486
Seizures in Infants Hospitalized in Pediatric Intensive Care Unit for Bronchiolitis No drug interventions Not Available Not Available completed NCT03557957
Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia No drug interventions treatment Not Available active_not_recruiting NCT01879774
Characterisation of Neuropsychological and Motoric Performance in Patients With Hyponatremia No drug interventions diagnostic Not Available completed NCT02442674
A Trial of Tolvaptan in Children and Adolescent Subjects With Euvolemic and Hypervolemic Hyponatremia treatment 3 withdrawn NCT02709031
Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium treatment 1 / 2 unknown_status NCT01748331
The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia No drug interventions treatment Not Available unknown_status NCT04561531
Efficacy and Safety of Bolus Comparing With Continuous Drip of 3% NaCl in Patients With Severe Symptomatic Hyponatremia. No drug interventions treatment Not Available unknown_status NCT01370473
Institutional Registry of Hyponatremia No drug interventions Not Available Not Available completed NCT04552873
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage treatment Not Available recruiting NCT02012660
Relationship Between Heat Wave and Hyponatremia No drug interventions Not Available Not Available completed NCT00201994
"SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia treatment 3 completed NCT00728091
A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia treatment 3 terminated NCT02103491
Effects of Oral Salt Supplementation on Physical Performance During a Half-ironman No drug interventions basic_science Not Available completed NCT03265691
Hyponatremia in the Prevention of Hospitalized Patients Falls No drug interventions prevention Not Available completed NCT00435591
A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia treatment 4 completed NCT03840629
Fluid Tonicity and Hyponatraemia Post Surgery No drug interventions Not Available Not Available completed NCT02926989
Intravenous Fluids in Hospitalised Children treatment 4 completed NCT00478192
Study of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia treatment 3 completed NCT02936167
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children Not Available Not Available unknown_status NCT02242604
Characterization of Neuropsychologic and Physical Performance in Geriatric Patients With Hyponatremia. No drug interventions Not Available Not Available completed NCT01386372
Tolvaptan for In-hospital Hyponatremia treatment 2 terminated NCT04493268
HYPONATREMIA IN COVID-19 PATIENTS No drug interventions Not Available Not Available completed NCT01556646
Effect of Tolvaptan on Cognitive Function in Cirrhosis treatment 3 completed NCT06020495
Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia treatment 3 not_yet_recruiting NCT00578695
THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation treatment 3 completed NCT00264914
Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion No drug interventions treatment 3 completed NCT05815550
Delirium Related to Proton Pump Inhibitors Use No drug interventions Not Available Not Available completed NCT04402190
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status No drug interventions Not Available Not Available completed NCT00684164
Safety and Efficacy of Conivaptan for the Correction of Hyponatremia in Neurological Patients treatment 3 withdrawn NCT05277584
Analysis of Factors Determining Increase of Serum Sodium in Hyponatremic Patients No drug interventions Not Available Not Available completed NCT01456533
Copeptin in the Differential Diagnosis of Dysnatremia in Hospitalized Patients No drug interventions Not Available Not Available completed NCT06408077
Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges No drug interventions basic_science Not Available recruiting NCT00379847
An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia treatment 3 completed NCT06037928
Plasma Sodium and Sodium Administration in the ICU No drug interventions Not Available Not Available recruiting NCT01708811
Hyponatremia and Myometrium Contractility. An Invitro Study No drug interventions Not Available Not Available terminated NCT04447911
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia treatment 4 recruiting NCT01451411
A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic Hyponatremia treatment 3 terminated NCT04588207
Urea for Chronic Hyponatremia treatment 2 terminated NCT02614807
Protein Supplementation in Thiazide-induced Hyponatremia No drug interventions treatment Not Available withdrawn NCT00555685
Hypertonic Saline Solution in Heart Failure No drug interventions treatment 2 completed NCT00492037
Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia treatment 3 completed NCT06013800
Hyponatremia Volume Status Analysis by Point-of-care Ultrasound No drug interventions Not Available Not Available recruiting NCT00380575
Study of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic Hyponatremia treatment 3 completed NCT01509170
The Clinical and Laboratory Characteristics of Recurrent Drug- Related Hyponatremia No drug interventions Not Available Not Available unknown_status NCT04256499
Water Load Test Value for Hyponatremia No drug interventions Not Available Not Available completed NCT01909336
Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia treatment 3 completed NCT06277336
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD treatment Not Available recruiting NCT03703713
Colloid Osmotic Pressure and Osmolality in Hyponatremia Not Available Not Available terminated NCT02263586
Influence of Triathlon on the Electrolyte Balance No drug interventions Not Available Not Available completed NCT00885430
Pico-Salax Colonic Preparation Study: Quantifying Electrolyte and Volume Status Changes diagnostic 4 completed NCT00621348
Maintenance Intravenous Fluids in Children treatment 3 completed NCT02215148
Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients Not Available Not Available terminated NCT00636857
Postoperative Hyponatremia - Are There Gender Differences? No drug interventions treatment Not Available unknown_status NCT02432157
Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: No drug interventions prevention 1 / 2 unknown_status NCT04409626
Hyponatraemia and Mortality in Schizophrenic and Bipolar Patients: Protocol for a Bayesian Causal Inference Study No drug interventions Not Available Not Available unknown_status NCT04020926
Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function No drug interventions Not Available Not Available terminated NCT01341665
Subclassification of the Syndrome of Inappropriate ADH Secretion No drug interventions Not Available Not Available completed NCT01301274
0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Critically Ill Children treatment Not Available completed NCT00887627
Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function Not Available 1 completed NCT00264927
Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion No drug interventions treatment 3 completed NCT00851227
Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function Not Available 1 completed NCT01890694
Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia treatment 4 terminated NCT01326429
Frequency and Origin of Dysnatremias in the Emergency Department No drug interventions Not Available Not Available withdrawn NCT02449044
International, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia treatment 3 completed NCT00541944
Establishment of an Algorithm for a Clinical Classfication of Hypoosmolar Hyponatremia No drug interventions Not Available Not Available completed NCT01850940
Efficacy and Safety of Tolvaptan in Cirrhotic Patients With Hyponatremia Not Available Not Available completed NCT03202667
Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study treatment 2 / 3 completed NCT04227301
Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients No drug interventions Not Available Not Available recruiting NCT02545101
An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH No drug interventions Not Available Not Available completed NCT03636568
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) No drug interventions prevention Not Available completed NCT01227512
Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia treatment 3 terminated NCT00734214
Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial No drug interventions prevention 3 completed NCT02545114
Tolvaptan for Patients With Acute Neurological Injuries treatment Not Available terminated NCT06484608
Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery No drug interventions other Not Available completed NCT01008644
Do Changes in Plasma Osmolality Influence Ventilation? No drug interventions basic_science 0 completed NCT00072683
"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia treatment 3 completed