Dermatophytosis (DBCOND0014342)

Identifiers

Synonyms

Favus / Tinea Favosa / Tinea favosa (disorder) / Dermatophytosis, unspecified / Dermatophytosis of unspecified site / Dermatophytosis NOS / Dermatophytosis (disorder) / Tinea NOS / Tinea / Tinea infections / Tinea infection NOS / Tinea infection / Ringworm NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Miconazole	An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.	Cytochrome P450 2C9enzyme Cytochrome P450 2D6enzyme Cytochrome P450 3A4enzyme ATP-dependent translocase ABCB1transporter Lanosterol 14-alpha demethylasetarget Nitric oxide synthase 3target Nitric oxide synthase, inducibletarget Cytochrome P450 11B1, mitochondrialenzyme Cytochrome P450 2A6enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C19enzyme Cytochrome P450 2E1enzyme Nuclear receptor subfamily 1 group I member 2target Lanosterol 14-alpha demethylaseenzyme Aromataseenzyme Calcium-activated potassium channeltarget Voltage-gated Potassium Channelstarget Inward rectifier potassium channeltarget Voltage gated L-type calcium channeltarget Albumincarrier Cytochrome P450 2C8enzyme
Mometasone furoate	A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.	Glucocorticoid receptortarget Cytochrome P450 2C8enzyme Progesterone receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme
Tolnaftate	An antifungal agent used to treat various skin infections caused by fungi.	Squalene monooxygenasetarget Squalene monooxygenasetarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03098615	Study Evaluating the Effect of Jublia on Dermatophytomas	Efinaconazole	treatment	4	completed