Parkinsonism (DBCOND0017874)

Identifiers

Synonyms
Parkinsonism, unspecified / Parkinsonian Disorders / Parkinsonism (disorder) / Hypokinetic-rigid syndrome / Secondary parkinsonism, unspecified / Symptomatic parkinsonism (disorder) / Secondary parkinsonism (disorder) / Parkinson Disease, Secondary / Secondary parkinsonism

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amantadine
A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
Atropine
A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
Benzatropine
An anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
Hyoscyamine
An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
Levodopa
A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism.
Procyclidine
An antispasmodic drug used to treat parkinsonism of various types and in the treatment of extrapyramidal symptoms.
Profenamine
An antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02760108
Parkinson's Families ProjectNo drug interventionsNot AvailableNot Availablerecruiting
NCT02064543
Measurement of Gait Using Opal APDM and Gait Mat in ParkinsonismNo drug interventionsNot AvailableNot Availablecompleted
NCT03034564
A Randomized, Double-Blind, Placebo-Controlled Study of Droxidopa for Fatigue in Parkinson's Diseasetreatment4terminated
NCT05551377
Head-up Tilt Sleeping to Alleviate Orthostatic Hypotension, Supine Hypertension and Nocturia in Parkinson's DiseaseNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01581645
Mobilaser Study to Help With People Who Are Having Problems With Their GaitNo drug interventionstreatment0completed
NCT03826056
Neurology Inpatient Clinical Education TrialNo drug interventionshealth_services_researchNot Availablecompleted
NCT01246336
Exploratory Study Using Nanotechnology to Detect Biomarkers of Parkinson's Disease From Exhaled BreathNo drug interventionsNot AvailableNot Availablecompleted
NCT05954013
Advance Care Planning and Care Coordination for People With Parkinson's DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT00682513
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT04075318
Study of UB-312 in Healthy Participants and Parkinson's Disease PatientsNo drug interventionstreatment1completed
NCT02194816
Modifiable Variables in Parkinsonism (MVP)No drug interventionsNot AvailableNot Availablerecruiting
NCT00950196
Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasiatreatment4completed
NCT00745030
Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and ParkinsonismtreatmentNot Availableterminated
NCT04876326
Potential Use of Autologous and Allogeneic Mesenchymal Stem Cells in Patients With Multiple System AtrophyNo drug interventionstreatmentNot Availableunknown_status
NCT01329926
Molecular Analysis of Human Neural Stem CellsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04086160
Effects of Transcranial Direct Current Stimulation (tDCS) on Motor Function in Schizophrenia Patients and Individuals at Risk for Psychotic OnsetNo drug interventionstreatmentNot Availablerecruiting
NCT02214862
2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified ParkinsonismNo drug interventionsNot Available0completed
NCT05677529
Prodromal and Overt Parkinson's Disease Epidemiological Study in BrazilNo drug interventionsNot AvailableNot Availablerecruiting
NCT06501469
Biomarkers in Parkinsonian SyndromesNo drug interventionsNot AvailableNot Availablerecruiting
NCT00767546
Botulinum Toxin for Treatment of Seborrhic Dermatitis in Parkinsonian PatientsNo drug interventionstreatment1unknown_status
NCT03314610
Effect of Need to Void on Parkinsonian GaitNo drug interventionsNot AvailableNot Availablecompleted
NCT04929795
Effects of Music Beat on Motor Function in Individuals at Risk for Psychotic Onset and Schizophrenia PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT03130595
West Sweden Parkinson Objective Measurement Registry StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03924414
Trial of Parkinson's And Zoledronic Acidtreatment4recruiting
NCT03034538
An Open-Label Tolerability and Exploratory Efficacy Study of Zonisamide for Dyskinesias in Parkinson's Diseasetreatment4suspended
NCT02650843
Non-motor Symptoms and Brain Dopamine Transporter BindingNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06573866
Enhancement of Quality of Work And LifeNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT04518059
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other ParkinsonismNo drug interventionsNot AvailableNot Availablerecruiting
NCT05514106
MIBG in Aging and Neurologic DisordersNo drug interventionsdiagnostic4enrolling_by_invitation
NCT06032585
TRANSPARK_LONG: The Diagnostic Value of Early Transcranial Ultrasound in Patients With Extrapyramidal Diseases in a Swedish PopulationNo drug interventionsNot AvailableNot Availablerecruiting
NCT01453127
DaTSCAN Imaging in Aging and Neurodegenerative Diseasediagnostic4enrolling_by_invitation
NCT05834634
Ultrasound Changes of the Vagus Nerve in Patients With ParkinsonismNo drug interventionsNot AvailableNot Availablerecruiting
NCT05506891
Efficacy and Safety of Astragalus for Non-motor Symptoms of α-SynucleinopathyNo drug interventionstreatment2recruiting
NCT05127057
Proactive and Integrated Management and Empowerment in Parkinson's Disease (PRIME-UK): A New Model of Care (PRIME-RCT)No drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT03421899
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular "Powerhouse") DysfunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT05308485
Events Exposure as a Trigger of the Clinical Manifestations of Parkinson's DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04553835
Effects of Rhythmic Auditory Stimulation on Movements in Individuals at Risk for Psychotic Onset and Schizophrenia PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT04238000
Cerebellar rTMS Theta Burst for Dual-task Walking in Parkinson's DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT04237948
tDCS Plus Physical Therapy for Progressive Supranuclear PalsyNo drug interventionstreatmentNot Availablecompleted
NCT04222218
Cerebellar rTMS Theta Burst for Postural Instability in Progressive Supranuclear PalsyNo drug interventionstreatmentNot Availablecompleted
NCT03495024
Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlatestreatment4unknown_status
NCT03386669
Novel Neuroimage Study in Tauopathies With Parkinsonismdiagnostic2completed
NCT03076671
More Than a Movement Disorder: Applying Palliative Care to Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01888185
Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)No drug interventionsNot AvailableNot Availablecompleted
NCT01174771
Repetitive Transcranial Magnetic Stimulation (TMS) for Progressive Supranuclear Palsy and Corticobasal DegenerationNo drug interventionsNot AvailableNot Availablecompleted